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Article: A coding variant in TMC8 (EVER2) is associated with high risk HPV infection and head and neck cancer risk.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Liang C; Kelsey KT; McClean MD; Christensen BC; Marsit CJ; Karagas MR; Waterboer T; Pawlita M; Nelson HH
PLoS ONE, 2015


10.1371/journal.pone.0123716.t003 Association between <italic>TMC8</italic> genotype and risk of HNSCC.
All sites Oral cavity Pharynx Larynx
TMC8 genotype na ORb (95% CI) na ORb (95% CI) na ORb (95% CI) na ORb (95% CI)
AA 113/142 referent 113/64 referent 113/52 referent 113/26 referent
AT 278/212 0.63 278/83 0.56 278/91 0.69 278/38 0.64
(0.45-0.89) (0.36-0.87) (0.44-1.04) (0.34-1.21)
TT 144/88 0.54 144/31 0.42 144/41 0.60 144/16 0.49
(0.36-0.81) (0.24-0.73) (0.35-1.01) (0.23-1.07)

a cases/controls.

b All OR’s adjusted for sex, age, packyears smoked and average drinks per week.


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